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Altogen Biosystems' Xenograft Models for Transfection Research

Altogen Biosystems is a recognized provider and laboratory for the pharmaceutical industry. Custom research services and additional goods include xenografts, cell transfection optimization, 28-day generation of stably-transfected cells, IND applications and more. Dedicated to assisting customers with cutting-edge and efficient services, Altogen Biosystems endeavors to advance modern laboratory techniques. Visit the official website for a Caki-1 xenograft model.

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Kidney Cancer Research Through Caki-1 Cells

Clear-cell carcinomas are some of the most common renal cancers observed in humans. Current medical efforts at finding cures to the cancer focus on the responses of it to the inhibition of  RAF-1, VEGR and PDGFR, all found in the Caki-1 cell line. Through transfection experiments with appropriate reagents , researchers can examine the possibilities of genetic modification and its ramifications on the physiology of Caki-1, leading to reliable results that can inform preclinical trials and commercial drug development.
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Caki-1 Transfection Reagent (Kidney Epithelial Cells)

The Caki-1 cell line was established from the renal carcinoma cells of a 49-year-old male patient with clear cell carcinoma. Caki-1 cells contain many microvilli, small mitochondria,and well developed endoplasmic reticulum (ER) and golgi apparatus. This cell line is not commercially available and is only available for research purposes. Transfection of the Caki-1 cell is facilitated by Caki-1 transfection reagents ( Altogen biosystems )  to establish stable cell lines, produce consistent research and to optimize transfection of siRNA, miRNA and pDNA.  Caki-1 Transfection Reagent (Kidney Epithelial Cells)
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Caki-1 Cell Line

Caki-1 is a tumorigenic cell line that was established from the cells of a renal tumor taken from a 49-year-old Caucasian male with clear cell carcinoma. Caki-1 cells have a modal chromosome number of 68, exhibit an epithelial-like morphology, and grow adherently in monolayers in vitro . The Caki-1 cell line is suitable for both in vivo and in vitro transfection to study kidney cancer, and a Caki-1 xenograft model and Caki-1 Transfection Reagent to transfect Caki-1 cells are available through Altogen Biosystems .
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